Antimicrobial resistance is a major public health issue that contributes to the emergence of drug-resistant microorganisms, thereby increasing the risk of nosocomial infections. Short peptide ...
Antibiotics are widely used in clinical treatment and animal production as an effective means to combat microbial infections. Antimicrobial peptides, as potential alternatives to antibiotics, have ...
A team of microbiologists, chemists and pharmaceutical specialists at Shandong University, Guangzhou Medical University, Second Military Medical University and Qingdao University, all in China, has ...
National University of Singapore (NUS) pharmaceutical scientists have developed synthetic peptide nanonets for treating infections by bacteria strains resistant to last-resort antibiotics. In nature, ...
New research into antimicrobial peptides, small chains of amino acids able to damage bacterial cells, shows why some peptides are more effective at doing that and also why some cells are more ...
A common infection-causing bacteria was much less likely to evolve antibiotic resistance when treated with a mixture of antimicrobial peptides rather than a single peptide, making these mixtures a ...
The story of antimicrobial peptides (AMPs), particularly in tackling antibiotic resistance, has been one of false dawns and unfulfilled promises. But perhaps a new generation of “smarter” compounds ...
In the summer of 1928, Alexander Fleming, an English biologist, accidentally discovered that the mold Penicillium notatum inhibits bacterial growth. Fleming’s serendipitous finding brought ...
The VDR is a member of the steroid/hormone nuclear receptor superfamily that includes 48 ligand-activated transcription factors. [3] These factors bind to conserved elements in the promoters of genes ...