Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumor-suppressing pathways, opening up new avenues for blood cancer ...

A new gene-editing technique enables the correction of multiple genetic mutations simultaneously, transforming the prospects ...

Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led ...

The gene p53 acts as a tumor suppressor and is often called the guardian of the genome. This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading to ...

Gear-obsessed editors choose every product we review. We may earn commission if you buy from a link. Why Trust Us? Without 8 or 9 hours of sleep, most of us end up staggering around like zombies. But ...

Despite the significance of immune checkpoint inhibitors (ICIs) in solid tumor treatment, identifying ICI-sensitive populations remains a challenge. Mutations in DNA damage response (DDR) pathway ...

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules.

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

GLOBAL: Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumour-suppressing pathways, opening up new avenues for blood cancer ...