Background: Survivors of cancer in adolescence and young adulthood are at increased risk for subsequent primary neoplasms, but studies using Canadian data are limited. We sought to quantify the risk ...

A 67-year-old man with a history of type 2 diabetes, diabetic peripheral neuropathy, and hypertension presents to the emergency department with a skin ulceration on the bottom of his great toe ...

A 16-year-old adolescent boy presented to the emergency department after a noncontact injury to his right leg during a basketball game. He reported landing with excessive internal rotation in knee ...

Access to health care: Inuit experiences of and expertise on the 21st-century tuberculosis epidemic in Nunavik, Quebec: a qualitative community-based participatory study ...

Key points A 69-year-old man presented to a dermatology clinic with a 1-day history of a painful erythematous rash. Four days ...

See related article at Key points In this issue of CMAJ , Geboe and colleagues present the results of a qualitative community-based participatory study of Inuit experiences of the ongoing epidemic of ...

Cognitive impairment occurs in 34% to 65% of people with MS,[1][1] with an elevated prevalence in those with disease of many years’ duration, heightened physical disability, and progressive illness ...

Background: Although brain and heart conditions share overlapping risk factors and commonly co-occur, current cardiac and neurologic clinical guidelines are typically produced within specialty silos.

Key points Sickle cell disease (SCD) occurs when a DNA base pair substitution in the β-globin gene results in the formation of hemoglobin S, which polymerizes when deoxygenated, leading to deformation ...

Key points A major armed conflict involving Canada or its North Atlantic Treaty Organization (NATO) allies, including coalition ground combat with large-scale casualty repatriation to Canadian ...

Clinical practice guideline for management of osteoporosis and fracture prevention in Canada: 2023 update Hypertension Canada guideline for the diagnosis and treatment of hypertension in adults in ...