Scientists from Skoltech and the University of Potsdam have developed a physical theory that sheds light on how molecular ...

Within the realm of genetic regulation, chromatin modifications such as histone methylation and acetylation play pivotal roles in the transcriptional control of genes. Disruptions in these processes ...

The human genome is about two meters long, yet it fits inside a nucleus only ~10 micrometers in diameter. A research team led ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study ...

DNA inside the nucleus is not packed as a rigid regular fiber—linker histone H1 dynamically binds and loosely "glues" ...

AMES, Iowa – In their long strings of nucleotides, DNA molecules hold massive troves of genetic data providing instructions for how living organisms should function – the blueprint of life. How the ...

Every cell in your body faces the same engineering puzzle: how to cram roughly two meters of DNA into a nucleus just a few ...