aState Key Laboratory of Female Fertility Promotion, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China bNational ...

Abstract: A reflection-mode quantitative phase microscope with automated scanning is applied for wide-field observation of migrasomes from unlabeled cells. By culturing cells on a silicon wafer with a ...

Migrasomes are newly discovered organelles that feature small vesicles enclosed within cavities [1]. The formation of migrasomes is intrinsically linked to cell migration, during which retraction ...

A group of Chinese researchers has found that viruses are using a technique strikingly similar to the Trojan Horse—unknown until now—to infiltrate and spread within the body. At different stages of ...

Background: Ischemic stroke leads to substantial disruption of the neurovascular unit (NVU), compromising neuronal viability and vascular integrity. Migrasomes, a novel class of extracellular vesicles ...

Background: Astrocytes are key regulators of central nervous system homeostasis, but how they adapt to ischemic injury is unclear. Migrasomes (Migs）are large (0.5–3 μm) vesicular organelles budding ...

OBJECTIVE: It has been previously shown that brain-derived neurotrophic factor is linked with various types of cancer. Brain-derived neurotrophic factor is found to be highly expressed in multiple ...

Scientists have uncovered a surprising viral shortcut that turns moving cells into delivery vehicles for infection. Instead of spreading one virus at a time, infected cells bundle viral material into ...

Viruses are known to spread efficiently between cells, but a new study reveals an unexpected pathway that links viral transmission to cell migration. Researchers discovered that vesicular stomatitis ...

Outstanding fundamental phenomenon (migrasomes) en route to become transitionally highly significant. Strengths: Innovative approach at several levels: Migrasomes, discovered by DR. Yu's group, are an ...

This study, from the group that pioneered migrasome, describes a novel vaccine platform of engineered migrosomes that behave like natural migrasomes. Importantly, this platform has the potential to ...

Generative mechanism of migrasome. Migrasome biogenesis can be divided into two steps: (i) the initial sites formation includes the generation of SMS2 foci, the recruitment of PIP5K1A, the formation ...