
Transforming growth factor - Wikipedia
The name transforming growth factor is somewhat arbitrary because the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms.
TGF-β signaling in health, disease and therapeutics
Mar 22, 2024 · Transforming growth factor (TGF)-β is a multifunctional cytokine expressed by almost every tissue and cell type. The signal transduction of TGF-β can stimulate diverse cellular responses …
TGF-beta signal transduction: biology, function and therapy for ...
Dec 22, 2022 · The transforming growth factor beta (TGF-β) is a crucial cytokine that get increasing concern in recent years to treat human diseases. This signal controls multiple cellular responses …
TGF-β signaling in health and disease: Cell
Sep 14, 2023 · Here, we review how TGF-β coordinates multicellular response programs in health and disease and how this knowledge can be leveraged to develop treatments for diseases of the TGF-β …
Transforming growth factor beta - Wikipedia
TGF-beta is a cytokine with three different isoforms, which regulates many cellular functions including cell proliferation, differentiation, adhesion and migration.
Transforming Growth Factor - an overview | ScienceDirect Topics
Transforming growth factor (TGF) is defined as a member of a superfamily of growth factors that modulate various processes involved in embryonic development and organogenesis, including …
TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and …
The transforming growth factor-β (TGF-β) is the prototype of the TGF-β family of growth and differentiation factors, which is encoded by 33 genes in mammals and comprises homo- and …
What Does TGF Beta Do? Roles in Growth, Repair, and Health
Apr 29, 2025 · Transforming Growth Factor Beta (TGF-β) is a multifunctional protein that regulates cell behavior, tissue development, and immune responses. While essential for normal physiological …
Transforming growth factor-β receptors: versatile mechanisms
Feb 13, 2024 · Transforming growth factor-β (TGF-β) signaling is initiated by activation of transmembrane TGF-β receptors (TGFBR), which deploys Smad2/3 transcription factors to control …
TGF alpha - Wikipedia
TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may …