Gene editing & lipid metabolism --- The investigation of how different metabolic pathways are regulated in health and disease is challenging. In particular, lipidomics still lacks specificity in defining which enzymes and proteins are responsible for generating and regulating different lipid species. Spiegel and collaborators developed a systematic screening approach that combines lipidomic analysis with CRISPR/Cas9-based gene knockout involved in lipid metabolism in the human colorectal carcino